MARS® system

With early intervention, MARS (Molecular Adsorbent Recirculating System) provides liver support and helps prevent the evolution of multiorgan failure contributing to an improved environment for hepatic regeneration and clinical recovery. MARS removes protein-bound and water-soluble toxins with albumin dialysis. This reduces plasma toxicity, improves patient clinical conditions (hemodynamics, hepatic encephalopathy, urine output), enhances the regeneration of liver cells and may help to recover native liver functions.

Clinically applied since 1993, the MARS system is the most extensively used non-biological liver support therapy in the world, with an ever-growing base of clinical experience and evidence covering more than 8,000 patients from 150 centers in 30 different countries. The MARS system is compatible with several standard hemodialysis machines and CRRT devices, and requires minimal staff involvement before and during treatment.

In the U.S., the MARS system is cleared for use in the treatment of drug overdose and poisonings only. It is not indicated in the U.S. for the treatment of chronic liver conditions or as a bridge to liver transplant.